Reply to Liu et al.: HNF4A and PTBP1 expression in the brain of neurodegenerative disease patients
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منابع مشابه
Reply to Liu et al.: HNF4A and PTBP1 expression in the brain of neurodegenerative disease patients.
We thank Liu et al. (1) for their comments on our manuscript in which hepatocyte nuclear factor 4 alpha (HNF4A) and polypyrimidine tract binding protein 1 (PTBP1) are identified as potential dynamic biomarkers for Parkinson’s disease (PD) (2). In our study, transcriptomic and network-based metaanalysis identified HNF4A and PTBP1 as the most significant up-regulated and down-regulated genes, res...
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We thank Liu et al. (1) for their comments on our work on the link between the cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL)-related protease high temperature requirement protein A1 (HtrA1) and the TGF-β signaling pathway. To advance our understanding of the mechanisms underlying HtrA1 deficiency, we used dermal fibroblasts from CARASIL pa...
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In a letter to the editor, Liu et al. (1) find that PTEN contains some transcript variants that are polyadenylated and prematurely terminated in the first intron of PTEN. These transcripts are suggested to be 5′-UTR– containing promoter-spanning and to encode for three small RNAs (sRNAs), with one of these (sRNA3) being antisense to oligodeoxynucleotide 2 (ODN2), which was one of two ODNs used ...
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In the last issue, I presented a piece that called into question some of the techniques reported in two papers in high-profile journals that purported to provide statistical evidence for the linguistic status of some ancient symbol systems (Sproat 2010a). Not surprisingly the authors of those two papers took issue with a number of my claims, and have requested the opportunity to respond. The tw...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2015
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1510113112